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Floxin

Generic Name: ofloxacin
Brand Name: Floxin

Indications

Floxin Tablets are indicated for the treatment of adults with mild to moderate infections (unless otherwise indicated) caused by susceptible strains of the designated microorganisms in the infections.

Dosage and Administration

Floxin Tablets are supplied as 200 mg, 300 mg e, and 400 mg tablets.

Normal Dosage:
The usual dose of FLOXIN® (ofloxacin tablets) Tablets is 200 mg to 400 mg orally every 12 h

Overdose: The most common symptom of an overdose is seizures.

Drug Description

Floxin Tablets is a synthetic broad-spectrum antimicrobial agent for oral administration. Chemically, ofloxacin, a fluorinated carboxyquinolone, is the racemate, (±)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. The chemical structure is:


FLOXIN®  (Ofloxacin Tablets) Structural Formula Illustration

Its empirical formula is C18H20FN3O4, and its molecular weight is 361.4

Side Effects
If you experience any of the following serious side effects, stop taking this medication and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction
  • seizures
  • confusion or hallucinations
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort)
  • muscle or joint pain

Precautions

  • Avoid excessive exposure to sunlight. Increases the sensitivity of the skin to sunlight, and severe sunburn may result. If exposure to the sun is unavoidable, wear protective clothing and sunscreen. Call your doctor if you experience swelling, redness, or a rash after exposure to sunlight.
  • Use caution when driving, operating machinery, or performing other hazardous activities.
  • Some medical conditions may interact with Floxin. Tell your doctor if you have any medical conditions, especially if any of the following apply to you:
    • if you are taking any prescription or nonprescription medicine,or dietary supplement
    • if you have allergies to medicines, food, or other substances
    • if you have diabetes, kidney problems, liver problems, or a recent heart attack
    • if you have Alzheimer disease, hardening of the arteries in the brain, seizures, increased pressure on the brain, or another central nervous system disorder
    • if you have tendonitis
    • if your skin is sensitive to sunlight

Drug Interactions

  • Avoid taking medicines for heart rhythm disturbances (eg, amiodarone, procainamide, quinidine, sotalol) because this may increase the risk of irregular heartbeat.
  • Avoid taking Corticosteroids (eg, prednisone) because this may increase the risk of having tendon problems.
  • Insulin or other medicines for diabetes (eg, glipizide) may increase the risk of low blood sugar.
  • Taking live typhoid vaccine may reduce the effectiveness of this drug.
 

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