Ansaid

Generic Name: Flurbiprofen
Brand Name: Ansaid

Indications
Ansaid is used for the relief and symptoms of rheumatoid arthritis and osteoarthritis.

Dosage and Administration

Ansaid is available as 50mg and 100mg tablets.

Normal Dosage: recommended is 200mg to 300 mg dividedly administering twice or thrice daily.
It is recommended to take the lowest effective dose for the shortest duration consistent with individual patient treatment goals. After observing the response to initial dosages, the dose and frequency should be adjusted to suit an individual patient's needs.

Overdose?

Overdose can result in lethargy, drowsiness, nausea, vomiting, and epigastric pain. At times over dosage can even lead to Hypertension, acute renal failure, respiratory depression.

Drug Description

ANSAID Tablets contain flurbiprofen, which is a member of the phenylalkanoic acid derivative group of nonsteroidal antiinflammatory drugs. ANSAID Tablets are white, oval, filmcoated tablets for oral administration. Flurbiprofen is a racemic mixture of (+)S- and (-)R- enantiomers. Flurbiprofen is a white or slightly yellow crystalline powder. It is slightly soluble in water at pH 7.0 and readily soluble in most polar solvents. The chemical name is [1,1'-biphenyl]-4-acetic acid, 2-fluoro-alpha-methyl-, (±)-. The molecular weight is 244.26. Its molecular formula is C15H13FO2 and it has the following structural formula:

The inactive ingredients in ANSAID (both strengths) include carnauba wax, colloidal silicon dioxide, croscarmellose sodium, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, propylene glycol, and titanium dioxide. In addition, the 100 mg tablet contains FD&C Blue No. 2.

Side Effects

Common side effects so far reported are edema, hypertension, abdominal pain, constipation, diarrhea, nausea, vomiting, body weight changes, and sometimes even urinary tract infections.

Precautions

• Take the lowest effective dose for the shortest duration and adjust the dosage and frequency of the medicine accordingly.
• In case of any liver disease should be notified to the doctor before administering the medicine to avoid further complications.
• Ansaid should not be administered to patients with preexisting asthma.
• Try avoiding the usage of Ansaid in late pregnancy.
• Safety and effectiveness of this medicine in pediatric patients have not been established

Drug Interactions

Notify your physician if you are administering on any of the following drugs before taking this medication

• Aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's)
• Any other nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), ibuprofen (Motrin, Advil), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Anaprox, others), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin)
• An anticoagulant (blood thinner) such as warfarin (Coumadin)
• A steroid such as prednisone (Deltasone)
• Insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase)
• Probenecid (Benemid)
• Lithium (Eskalith, Lithobid)

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